N-bromobutanimide → HCID 58181342, compound

HRID 1465459Notes

Reaction equation

HRID 1465459 reaction equation
[C:1]([N:4]1[CH2:9][CH2:8][N:7]([C:10]2[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=2)[CH2:6][CH2:5]1)(=[O:3])[CH3:2].[Br:16]N1C(=O)CCC1=O>>[C:1]([N:4]1[CH2:5][CH2:6][N:7]([C:10]2[CH:11]=[N:12][C:13]([Br:16])=[CH:14][CH:15]=2)[CH2:8][CH2:9]1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 67184N-bromobutanimideHCID 59628451HCID 59628451, compound

Product 1

HCID 58181342HCID 58181342, compound

Procedure

1-Acetyl-4-(6-bromopyridin-3-yl)piperazine was synthesized from above-mentioned 1-acetyl-4-pyridin-3-ylpiperazine by brominating with N-bromosuccinimide by a method similar to Production Example 86, step 2,

Sources & evidence

ORD record
ord-f4c3c2a62c8a4cf39233c268184c30b8
Source dataset
uspto-grants-2015_04
Patent number
US08999989B2

Reaction notes

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