HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → methyl (2E)-3-[4-(hydroxymethyl)thiophen-2-yl]prop-2-enoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | methyl (2E)-3-(4-formylthiophen-2-yl)acrylate | HCID 86650009 | — |
| Product | methyl (2E)-3-[4-(hydroxymethyl)thiophen-2-yl]prop-2-enoate | HCID 67030186 | 92.6% |
Reaction Steps
By a method similar to Production Example 120, step 1, methyl (2E)-3-(4-formylthiophen-2-yl)prop-2-enoate (1.700 g, 8.664 mmol) was reduced with sodium borohydride to give methyl (2E)-3-[4-(hydroxymethyl)thiophen-2-yl]prop-2-enoate (1.591 g, yield 92.6%) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08999989B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-83414a59bf24466cbb4c927d550ae165 |
| Source note | uspto-grants-2015_04 |