HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisobutylaluminumhydride → HCID 67030545, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisobutylaluminumhydride | HCID 21225700 | — |
| Reactant | HCID 67030331 | HCID 67030331 | — |
| Product | HCID 67030545 | HCID 67030545 | 80.2% |
Reaction Steps
By a method similar to Production Example 113, step 5, tert-butyl 4-(6-{2-[5-(3-methoxy-3-oxopropyl)thiophen-3-yl]ethyl}pyridin-3-yl)piperazine-1-carboxylate (840.0 mg, 1.828 mg) was reduced with diisobutylaluminum hydride to give tert-butyl 4-(6-{2-[5-(3-hydroxypropyl)thiophen-3-yl]ethyl}pyridin-3-yl)piperazine-1-carboxylate (632.3 mg, yield 80.1%) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08999989B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-fb7987bcc0b74113807299091b47f5d3 |
| Source note | uspto-grants-2015_04 |