Dimethyl Sulfoxide → methyl 3,5-difluoro-4-[4-(2-fluorophenyl)-3-[[(2-methylpropan-2-yl)oxycarbonyl-(1-naphthalen-1-ylethyl)amino]methyl]piperidin-1-yl]benzoate
Reaction equation
[C:48](=[O:49])([O-:50])[O-:51].[CH3:54][S:55]([CH3:56])=[O:57].[F:1][c:2]1[c:3]([CH:8]2[CH:9]([CH2:14][N:15]([C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[CH:23]([CH3:24])[c:25]3[cH:26][cH:27][cH:28][c:29]4[cH:30][cH:31][cH:32][cH:33][c:34]34)[CH2:10][NH:11][CH2:12][CH2:13]2)[cH:4][cH:5][cH:6][cH:7]1.[F:35][c:36]1[cH:37][c:38]([C:39](=[O:40])[O:41][CH3:42])[cH:43][c:44]([F:47])[c:45]1[F:46].[K+:52].[K+:53].[OH2:58]>>[F:1][c:2]1[c:3]([CH:8]2[CH:9]([CH2:14][N:15]([C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[CH:23]([CH3:24])[c:25]3[cH:26][cH:27][cH:28][c:29]4[cH:30][cH:31][cH:32][cH:33][c:34]34)[CH2:10][N:11]([c:45]3[c:36]([F:35])[cH:37][c:38]([C:39](=[O:40])[O:41][CH3:42])[cH:43][c:44]3[F:47])[CH2:12][CH2:13]2)[cH:4][cH:5][cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-051c1094f40a4bd8bb3ea9d307bceb2d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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