HCID 86607504, compound → HCID 67233450, compound

HRID 1465926Notes

Reaction equation

HRID 1465926 reaction equation
C(OC(C1C(O)=C2C=C(C3C=CC(OC)=CC=3)SC2=C(Cl)N=1)=O)CCC.[CH2:27]([O:31][C:32]([C:34]1[N:39]=[C:38](Cl)[C:37]2[CH:41]=[C:42]([C:44]3[CH:49]=[CH:48][C:47]([O:50][CH3:51])=[CH:46][CH:45]=3)[S:43][C:36]=2[C:35]=1[OH:52])=[O:33])[CH2:28][CH2:29][CH3:30]>>[CH2:27]([O:31][C:32]([C:34]1[N:39]=[CH:38][C:37]2[CH:41]=[C:42]([C:44]3[CH:45]=[CH:46][C:47]([O:50][CH3:51])=[CH:48][CH:49]=3)[S:43][C:36]=2[C:35]=1[OH:52])=[O:33])[CH2:28][CH2:29][CH3:30]

Participants

3

Reactant 2

HCID 86607504HCID 86607504, compoundHCID 86607505HCID 86607505, compound

Product 1

HCID 67233450HCID 67233450, compound

Procedure

The title compound was prepared from a mixture of 7-chloro-4-hydroxy-2-(4-methoxy-phenyl)-thieno[2,3-c]pyridine-5-carboxylic acid butyl ester and 4-chloro-7-hydroxy-2-(4-methoxy-phenyl)-thieno[3,2-c]pyridine-6-carboxylic acid butyl ester, example 3-c, analogously to experimental conditions for example 1-g; with isolation of the higher Rf isomer. MS: (+) m/z 358.05 (M+1).

Sources & evidence

ORD record
ord-916b1fc9b63f4ded8e9edfcd0ca00764
Source dataset
uspto-grants-2015_04
Patent number
US09000006B2

Reaction notes

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