HCID 86607506, compound → HCID 67233501, compound

HRID 1465929Notes

Reaction equation

C(OC(C1N=C(Br)C2C=C(C3C=CC(OC4C=CC=CC=4)=CC=3)SC=2C=1O)=O)CCC.[CH2:32]([O:36][C:37]([C:39]1[C:40]([OH:62])=[C:41]2[CH:48]=[C:47]([C:49]3[CH:54]=[CH:53][C:52]([O:55][C:56]4[CH:61]=[CH:60][CH:59]=[CH:58][CH:57]=4)=[CH:51][CH:50]=3)[S:46][C:42]2=[C:43](Br)[N:44]=1)=[O:38])[CH2:33][CH2:34][CH3:35]>>[CH2:32]([O:36][C:37]([C:39]1[C:40]([OH:62])=[C:41]2[CH:48]=[C:47]([C:49]3[CH:54]=[CH:53][C:52]([O:55][C:56]4[CH:57]=[CH:58][CH:59]=[CH:60][CH:61]=4)=[CH:51][CH:50]=3)[S:46][C:42]2=[CH:43][N:44]=1)=[O:38])[CH2:33][CH2:34][CH3:35]

Participants

Reactant 2

HCID 86607506HCID 86607506, compound

HCID 86607507HCID 86607507, compound

Product 1

HCID 67233501HCID 67233501, compound

Procedure

The title compound was prepared from a mixture of 4-bromo-7-hydroxy-2-(4-phenoxy-phenyl)-thieno[3,2-c]pyridine-6-carboxylic acid butyl ester and 7-bromo-4-hydroxy-2-(4-phenoxy-phenyl)-thieno[2,3-c]pyridine-5-carboxylic acid butyl ester, example 7-c, under conditions analogous to experimental example 13-a with isolation of the lower Rf isomer. MS: (+) m/z 420.06 (M+1).

Sources & evidence

ORD record: ord-69346eb05a6d4f46b40b3593e05a7213
Source dataset: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09000006B2

Reaction notes

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