3-(Trifluoromethyl)phenylboronic acid → HCID 67232853, compound

HRID 1465940Notes

Reaction equation

HRID 1465940 reaction equation
[F:1][C:2]([F:13])([F:12])[C:3]1[CH:4]=[C:5](B(O)O)[CH:6]=[CH:7][CH:8]=1.[CH2:14]([O:16][C:17]([C:19]1[N:24]=[CH:23][C:22]2[CH:25]=[C:26](Br)[S:27][C:21]=2[C:20]=1[OH:29])=[O:18])[CH3:15]>>[CH2:14]([O:16][C:17]([C:19]1[N:24]=[CH:23][C:22]2[CH:25]=[C:26]([C:5]3[CH:6]=[CH:7][CH:8]=[C:3]([C:2]([F:13])([F:12])[F:1])[CH:4]=3)[S:27][C:21]=2[C:20]=1[OH:29])=[O:18])[CH3:15]

Participants

3

Reactant 2

HCID 27343883-(Trifluoromethyl)phenylboronic acidHCID 67233406HCID 67233406, compound

Product 1

HCID 67232853HCID 67232853, compound

Procedure

The title compound was prepared from 3-(trifluoromethyl)phenyl boronic acid and 2-bromo-7-hydroxy-thieno[3,2-c]pyridine-6-carboxylic acid ethyl ester, example 21.d, under conditions analogous to experimental example 21.e; MS: (+) m/z 368.0 (M+1)

Sources & evidence

ORD record
ord-47437dd83a7241ecb9fb923480ec1310
Source dataset
uspto-grants-2015_04
Patent number
US09000006B2

Reaction notes

Loading…