HCID 178450841, compound → HCID 66861909, compound

HRID 1465957Notes

Reaction equation

HRID 1465957 reaction equation
C(O[C:6]([C:8]1[N:13]=[C:12](O)[C:11]2[CH:15]=[C:16]([C:18]3[CH:23]=[CH:22][C:21]([F:24])=[CH:20][CH:19]=3)[S:17][C:10]=2[C:9]=1[OH:25])=[O:7])CCC.C([O:30][C:31]([C:33]1C(O)=C2C=C(C3C=CC(F)=CC=3)SC2=C(O)[N:38]=1)=[O:32])CCC>>[F:24][C:21]1[CH:20]=[CH:19][C:18]([C:16]2[S:17][C:10]3[C:9]([OH:25])=[C:8]([C:6]([NH:38][CH2:33][C:31]([OH:32])=[O:30])=[O:7])[N:13]=[CH:12][C:11]=3[CH:15]=2)=[CH:23][CH:22]=1

Participants

3

Reactant 2

HCID 178450841HCID 178450841, compoundHCID 178450863HCID 178450863, compound

Product 1

HCID 66861909HCID 66861909, compound

Procedure

The title compound was prepared from 2-(4-fluoro-phenyl)-4,7-dihydroxy-thieno[3,2-c]pyridine-6-carboxylic acid butyl ester and 2-(4-fluoro-phenyl)-4,7-dihydroxy-thieno[2,3-c]pyridine-5-carboxylic acid butyl ester, example 34-b, under conditions analogous to experimental example 30-g. MS: (+) m/z 424.0, 425.9 (M+1, 79Br/81Br).

Sources & evidence

ORD record
ord-e7bfc704a35f4e608d93686c20f01ae6
Source dataset
uspto-grants-2015_04
Patent number
US09000006B2

Reaction notes

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