HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (1-oxo-1H-isochromen-6-yl)acetaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 6-(1,3-Dioxolan-2-ylmethyl)isochromen-1-one | HCID 77230659 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | (1-oxo-1H-isochromen-6-yl)acetaldehyde | HCID 77230658 | — |
Reaction Steps
To a solution of 6-(1,3-dioxolan-2ylmethyl)-1H-isochromen-1-one (410 mg, 1.8 mmol) in dioxane (20 mL) was added HCl (20 ml, 3M), and then stirred for 16 hours. The reaction was extracted with ethyl acetate then separated. The organic layer was washed with brine, dried over Na2SO4, filtered and concentrated to yield the title product. LC-MS (IE, m/z): 189 [M+1]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08999990B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-6973bd27dfa44dcfb8dd1af151a6fad7 |
| Source note | uspto-grants-2015_04 |