HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Methoxy-4-nitrophenyl)acetaldehyde → 1-[2-(2,1,3-Benzoxadiazol-5-yl)ethyl]-4-[2-(2-methoxy-4-nitrophenyl)ethyl]piperazin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Methoxy-4-nitrophenyl)acetaldehyde | HCID 11171558 | — |
| Reactant | 1-[2-(2,1,3-Benzoxadiazol-5-yl)ethyl]-2-piperazinone | HCID 89526184 | — |
| Product | 1-[2-(2,1,3-Benzoxadiazol-5-yl)ethyl]-4-[2-(2-methoxy-4-nitrophenyl)ethyl]piperazin-2-one | HCID 89533486 | — |
Reaction Steps
The title compound was prepared from 1-[2-(2,1,3-Benzoxadiazol-5-yl)ethyl]piperazin-2-one and (2-Methoxy-4-nitrophenyl)acetaldehyde following essentially the same procedure as Example 6. The product was purified by mass-directed reverse phase HPLC (AcCN-Water with 0.1% TFA). LC-MS (IE, m/z): 426 [M+1]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08999990B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-1b52206618d845f896a7589a0d27463f |
| Source note | uspto-grants-2015_04 |