HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Oxo-5,6,7,8-tetrahydronaphthalene-2-carbonitrile → (6S)-6,6'-(2-oxopiperazine-1,4-diyl)-di-(5,6,7,8-tetrahydronaphthalene-2-carbonitrile)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Oxo-5,6,7,8-tetrahydronaphthalene-2-carbonitrile | HCID 16244504 | — |
| Reactant | (6S)-6-(2-Oxopiperazin-1-yl)-5,6,7,8-tetrahydronaphthalene-2-carbonitrile | HCID 89524982 | — |
| Product | (6S)-6,6'-(2-oxopiperazine-1,4-diyl)-di-(5,6,7,8-tetrahydronaphthalene-2-carbonitrile) | HCID 89533513 | — |
Reaction Steps
The title compound was prepared from (6S)-6-(2-Oxopiperazin-1-yl)-5,6,7,8-tetrahydronaphthalene-2-carbonitrile and 6-Oxo-5,6,7,8-tetrahydronaphthalene-2-carbonitrile following essentially the same procedure as Example 6. The product was purified by mass-directed reverse phase HPLC (AcCN-Water with 0.1% TFA). LC-MS (IE, m/z): 411 [M+1]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08999990B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-bbf5e8df3d9447149a66e7043db9e1b8 |
| Source note | uspto-grants-2015_04 |