1-[2-(4-Nitrophenyl)ethyl]piperazin-2-one → HCID 89533480, compound

HRID 1466135Notes

Reaction equation

HRID 1466135 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][CH2:11][N:12]2[CH2:17][CH2:16][NH:15][CH2:14][C:13]2=[O:18])=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH3:19][C:20]1[CH:25]=[C:24]([N+:26]([O-:28])=[O:27])[CH:23]=[CH:22][C:21]=1[CH2:29][CH:30]=O>>[CH3:19][C:20]1[CH:25]=[C:24]([N+:26]([O-:28])=[O:27])[CH:23]=[CH:22][C:21]=1[CH2:29][CH2:30][N:15]1[CH2:16][CH2:17][N:12]([CH2:11][CH2:10][C:7]2[CH:8]=[CH:9][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=2)[C:13](=[O:18])[CH2:14]1

Participants

3

Reactant 2

HCID 895248911-[2-(4-Nitrophenyl)ethyl]piperazin-2-oneHCID 89525023HCID 89525023, compound

Product 1

HCID 89533480HCID 89533480, compound

Procedure

The title compound was prepared from 1-[2-(4-Nitrophenyl)ethyl]piperazin-2-one and (2-Methyl-4-nitrophenyl)acetaldehyde following essentially the same procedure as Example 6. The product was purified by mass-directed reverse phase HPLC (AcCN-Water with 0.1% TFA). LC-MS (IE, m/z): 413 [M+1]+.

Workup

  1. customThe product was purified by mass-directed reverse phase HPLC (AcCN-Water with 0.1% TFA)

Sources & evidence

ORD record
ord-51c2305b89b540e9b51c44bad47bd8b2
Source dataset
uspto-grants-2015_04
Patent number
US08999990B2

Reaction notes

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