HCID 87458432, compound → HCID 89533503, compound

HRID 1466138Notes

Reaction equation

HRID 1466138 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][CH2:11][N:12]2[CH2:17][CH2:16][NH:15][CH2:14][C:13]2=[O:18])=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH3:19][O:20][C:21]1[CH:22]=[C:23]([CH2:30][CH:31]=O)[CH:24]=[CH:25][C:26]=1[N+:27]([O-:29])=[O:28]>>[CH3:19][O:20][C:21]1[CH:22]=[C:23]([CH2:30][CH2:31][N:15]2[CH2:16][CH2:17][N:12]([CH2:11][CH2:10][C:7]3[CH:8]=[CH:9][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=3)[C:13](=[O:18])[CH2:14]2)[CH:24]=[CH:25][C:26]=1[N+:27]([O-:29])=[O:28]

Participants

3

Reactant 2

HCID 87458432HCID 87458432, compoundHCID 895248911-[2-(4-Nitrophenyl)ethyl]piperazin-2-one

Product 1

HCID 89533503HCID 89533503, compound

Procedure

The title compound was prepared from 1-[2-(4-Nitrophenyl)ethyl]piperazin-2-one and (3-Methoxy-4-nitrophenyl)acetaldehyde following essentially the same procedure as Example 6. The product was purified by mass-directed reverse phase HPLC (AcCN-Water with 0.1% TFA). LC-MS (IE, m/z): 429 [M+1]+.

Workup

  1. customThe product was purified by mass-directed reverse phase HPLC (AcCN-Water with 0.1% TFA)

Sources & evidence

ORD record
ord-330720ecb4cd451b9766f36eee2bf4ac
Source dataset
uspto-grants-2015_04
Patent number
US08999990B2

Reaction notes

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