Benzoic Acid → HCID 21313667, compound

Participants

Reaction Steps

To a solution of men- phenyl-1,3,4-oxadiazole-2-thiol and a benzoic acid in water was added NaOH. After stirring at RT for 16 h, the reaction mixture's pH was adjusted to 2 upon addition of aqueous solution of HCI (10%). The precipitate was collected by filtration. The solid was dissolved in acetone and purified by MPLC (30-70% ethyl acetate in hexanes) to afford the corresponding oxadiazol-benzoic acid.

Provenance & Evidence