Cesium carbonate → HCID 63753154, compound

HRID 1466399Notes

Reaction equation

HRID 1466399 reaction equation
Cl[C:2]1[N:6]([CH3:7])[N:5]=[C:4]([CH3:8])[C:3]=1[CH:9]=[O:10].[F:11][C:12]([F:21])([F:20])[C:13]1[CH:18]=[CH:17][C:16]([OH:19])=[CH:15][CH:14]=1.C(=O)([O-])[O-:23].[Cs+].[Cs+]>>[CH3:7][N:6]1[C:2]([O:19][C:16]2[CH:15]=[CH:14][C:13]([C:12]([F:20])([F:21])[F:11])=[CH:18][CH:17]=2)=[C:3]([C:9]([OH:10])=[O:23])[C:4]([CH3:8])=[N:5]1

Participants

4

Reactant 3

HCID 10796Cesium carbonateHCID 678744-(Trifluoromethyl)phenolHCID 27773975-Chloro-1,3-dimethylpyrazole-4-carboxaldehyde

Product 1

HCID 63753154HCID 63753154, compound

Procedure

The title compound was prepared using 5-chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde and 4-(trifluoromethyl)phenol in the manner similar to the method in Production Example 1 above except cesium carbonate was used instead of potassium hydroxide.

Sources & evidence

ORD record
ord-e76ef821e35f4522b4cd353d787c7cc9
Source dataset
uspto-grants-2015_04
Patent number
US09000024B2

Reaction notes

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