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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1466506Generated: November 4, 2026

Tetrahydro-4H-pyran-4-one → Necrox-7

https://huagongshe.com/reaction/1466506

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydro-4H-pyran-4-oneHCID 121599—
Reactant5-(1,1-Dioxo-thiomorpholin-4-yl)methyl-2-phenyl-7-nitro-1H-indoleHCID 68471868—
ProductNecrox-7HCID 44187164—

Reaction Steps

5-(1,1-Dioxo-thiomorpholin-4-yl)methyl-2-phenyl-7-nitro-1H-indole prepared in Step B and tetrahydropyran-4-one were reacted according to the same procedure as Example 1 to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000028B2
Source datasetuspto-grants-2015_04
ORD IDord-84f86300bfcf43ff8186fd0f5e538d23
Source noteuspto-grants-2015_04