1-Methyl-4-piperidone → HCID 25215915, compound

HRID 1466511Notes

Reaction equation

HRID 1466511 reaction equation
[CH:1]1([NH:6][C:7]2[CH:8]=[C:9]([Cl:23])[CH:10]=[C:11]3[C:15]=2[NH:14][C:13]([C:16]2[CH:21]=[CH:20][C:19]([NH2:22])=[CH:18][CH:17]=2)=[CH:12]3)[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:24][N:25]1[CH2:30][CH2:29][C:28](=O)[CH2:27][CH2:26]1>>[CH:1]1([NH:6][C:7]2[CH:8]=[C:9]([Cl:23])[CH:10]=[C:11]3[C:15]=2[NH:14][C:13]([C:16]2[CH:17]=[CH:18][C:19]([NH:22][CH:28]4[CH2:29][CH2:30][N:25]([CH3:24])[CH2:26][CH2:27]4)=[CH:20][CH:21]=2)=[CH:12]3)[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 740491-Methyl-4-piperidoneHCID 25215914HCID 25215914, compound

Product 1

HCID 25215915HCID 25215915, compound

Procedure

Cyclopentyl-[2-(4-aminophenyl)-5-chloro-1H-indol-7-yl]-amine prepared in Example 82 and 1-methyl-piperidin-4-one were reacted according to the same procedure as Step B of Example 1 to give the title compound.

Sources & evidence

ORD record
ord-76db2e945b3741618028d6f992842c51
Source dataset
uspto-grants-2015_04
Patent number
US09000028B2

Reaction notes

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