HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopentanone → 2-[(R)-2-(7-cyclopentylamino-2-phenyl-1H-indol-5-yl)-4,5-dihydro-thiazol-4-yl]-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopentanone | HCID 8452 | — |
| Reactant | 2-[(R)-2-(7-nitro-2-phenyl-1H-indol-5-yl)-4,5-dihydro-thiazol-4-yl]-acetic acid methyl ester | HCID 68476421 | — |
| Product | 2-[(R)-2-(7-cyclopentylamino-2-phenyl-1H-indol-5-yl)-4,5-dihydro-thiazol-4-yl]-acetic acid | HCID 68475793 | — |
Reaction Steps
2-[(R)-2-(7-nitro-2-phenyl-1H-indol-5-yl)-4,5-dihydro-thiazol-4-yl]-acetic acid methyl ester prepared in Step B and cyclopentanone were reacted according to the same procedures as Examples 1 and 30 to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09000028B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-06716d6964614533a5a30a62348ef68f |
| Source note | uspto-grants-2015_04 |