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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1466532Generated: October 31, 2026

Thiomorpholine 1,1-dioxide → HCID 68475957, compound

https://huagongshe.com/reaction/1466532

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThiomorpholine 1,1-dioxideHCID 6484228—
Reactant2-[3-(7-Tetrahydropyran-4-ylamino-5-chloro-1H-indol-2-yl)-phenyl]-acetic acid methyl esterHCID 68477733—
ProductHCID 68475957HCID 68475957—

Reaction Steps

2-[3-(7-Tetrahydropyran-4-ylamino-5-chloro-1H-indol-2-yl)-phenyl]-acetic acid methyl ester prepared in Example 132 and 1,1-dioxo-thiomorpholine were reacted according to the same procedures as Example 32 and Steps A and B of Example 36 sequentially to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000028B2
Source datasetuspto-grants-2015_04
ORD IDord-0709d1106a5d43b2a08fdd43d7eede5f
Source noteuspto-grants-2015_04