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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1466660Generated: November 1, 2026

Trifluoroacetic acid → HCID 70496855, compound

https://huagongshe.com/reaction/1466660

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 70495258HCID 70495258—
SolventDichloromethaneHCID 6344—
ProductHCID 70496855HCID 70496855—

Reaction Steps

Trifluoroacetic acid (10 mL) was added dropwise to a solution of tert-butyl 2-(3-(5-chloro-2-methoxyphenyl)-4-(pyrazolo pyrimidine-3-carboxamido)-1H-pyrazol-1-yl)propanoate (0.945 g, 1.90 mmol, 1 equiv) in dichloromethane (10 mL). After 2 h, the reaction mixture was concentrated in vacuo to afford crude product (quantitative) which was used without further purification. LCMS (ESI): M+H=441.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08999998B2
Source datasetuspto-grants-2015_04
ORD IDord-eaea4760c2cf4f3cabb180e67fa33f74
Source noteuspto-grants-2015_04