4-Fluorobenzyl bromide → HCID 66765331, compound

HRID 1466789Notes

Reaction equation

HRID 1466789 reaction equation
[CH3:1][O:2][C:3](=[O:22])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([S:10][C:11]2[C:19]3[C:14](=[CH:15][C:16]([Cl:20])=[CH:17][CH:18]=3)[NH:13][C:12]=2[CH3:21])[CH:5]=1.[F:23][C:24]1[CH:31]=[CH:30][C:27]([CH2:28]Br)=[CH:26][CH:25]=1>>[CH3:1][O:2][C:3](=[O:22])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([S:10][C:11]2[C:19]3[C:14](=[CH:15][C:16]([Cl:20])=[CH:17][CH:18]=3)[N:13]([CH2:28][C:27]3[CH:30]=[CH:31][C:24]([F:23])=[CH:25][CH:26]=3)[C:12]=2[CH3:21])[CH:5]=1

Participants

3

Reactant 2

HCID 680214-Fluorobenzyl bromideHCID 66765016HCID 66765016, compound

Product 1

HCID 66765331HCID 66765331, compound

Procedure

Prepared according to the procedure described in Example 4, Step 1, using the following starting materials: 3-(6-chloro-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid methyl ester and 4-fluorobenzyl bromide.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-458936a0c70b4d74a8ebd6830f9fd1d5
Source dataset
uspto-grants-2015_04
Patent number
US09000025B2

Reaction notes

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