5-Bromo-2-(trifluoromethyl)pyridine → HCID 66765425, compound

HRID 1466803Notes

Reaction equation

HRID 1466803 reaction equation
[CH3:1][O:2][C:3](=[O:22])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([S:10][C:11]2[C:19]3[C:14](=[CH:15][C:16]([Cl:20])=[CH:17][CH:18]=3)[NH:13][C:12]=2[CH3:21])[CH:5]=1.Br[C:24]1[CH:25]=[CH:26][C:27]([C:30]([F:33])([F:32])[F:31])=[N:28][CH:29]=1>>[CH3:1][O:2][C:3](=[O:22])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([S:10][C:11]2[C:19]3[C:14](=[CH:15][C:16]([Cl:20])=[CH:17][CH:18]=3)[N:13]([C:24]3[CH:29]=[N:28][C:27]([C:30]([F:33])([F:32])[F:31])=[CH:26][CH:25]=3)[C:12]=2[CH3:21])[CH:5]=1

Participants

3

Reactant 2

HCID 27611975-Bromo-2-(trifluoromethyl)pyridineHCID 66765016HCID 66765016, compound

Product 1

HCID 66765425HCID 66765425, compound

Procedure

Prepared according to the procedure described in Example 27, Step 1, using the following starting materials: 3-(6-chloro-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid methyl ester and 5-bromo-2-trifluoromethylpyridine.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-01311561dff449b58a0c65f8e78976fb
Source dataset
uspto-grants-2015_04
Patent number
US09000025B2

Reaction notes

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