HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Ethyl 3-bromo-4-methoxybenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 3-Bromo-4-methoxybenzoic acid | HCID 66836 | — |
| Product | Ethyl 3-bromo-4-methoxybenzoate | HCID 23062539 | — |
Reaction Steps
3-Bromo-4-methoxy-benzoic acid (2.5 g, 11.6 mmol) was dissolved in EtOH (20 mL) and conc. H2SO4 (1 mL) was added. The reaction was heated to reflux overnight then submitted to standard aqueous workup. The residue was purified by silica gel chromatography (0-50% EtOAc in hexanes) to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09000025B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-93cd1783997c4f829e87d3da859135cd |
| Source note | uspto-grants-2015_04 |