1H-Pyrazole, 4-bromo-1-methyl- → HCID 66764953, compound

HRID 1466819Notes

Reaction equation

HRID 1466819 reaction equation
[CH2:1]([O:3][C:4](=[O:25])[C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[C:7]([S:13][C:14]2[C:22]3[C:17](=[CH:18][C:19]([Cl:23])=[CH:20][CH:21]=3)[NH:16][C:15]=2[CH3:24])[CH:6]=1)[CH3:2].Br[C:27]1[CH:28]=[N:29][N:30]([CH3:32])[CH:31]=1>>[CH2:1]([O:3][C:4](=[O:25])[C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[C:7]([S:13][C:14]2[C:22]3[C:17](=[CH:18][C:19]([Cl:23])=[CH:20][CH:21]=3)[N:16]([C:27]3[CH:28]=[N:29][N:30]([CH3:32])[CH:31]=3)[C:15]=2[CH3:24])[CH:6]=1)[CH3:2]

Participants

3

Reactant 2

HCID 1674331H-Pyrazole, 4-bromo-1-methyl-HCID 66765076HCID 66765076, compound

Product 1

HCID 66764953HCID 66764953, compound

Procedure

Prepared according to the procedure described in Example 40, Step 6, using the following starting materials: 3-(6-chloro-2-methyl-1H-indol-3-ylsulfanyl)-4-methoxy-benzoic acid ethyl ester and 4-bromo-1-methylpyrazole.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-f61d40fac48a4d2ebf51251f2a209460
Source dataset
uspto-grants-2015_04
Patent number
US09000025B2

Reaction notes

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