m-Chlorophenylhydrazine hydrochloride → 3-(6-Chloro-2-methyl-1H-indol-3-ylsulfanyl)-5-methyl-benzoic acid ethyl ester

HRID 1466845Notes

Reaction equation

HRID 1466845 reaction equation
[CH2:1]([O:3][C:4](=[O:17])[C:5]1[CH:10]=[C:9]([S:11][CH2:12][C:13](=O)[CH3:14])[CH:8]=[C:7]([CH3:16])[CH:6]=1)[CH3:2].Cl.[Cl:19][C:20]1[CH:21]=[C:22]([NH:26]N)[CH:23]=[CH:24][CH:25]=1>>[CH2:1]([O:3][C:4](=[O:17])[C:5]1[CH:6]=[C:7]([CH3:16])[CH:8]=[C:9]([S:11][C:12]2[C:23]3[C:22](=[CH:21][C:20]([Cl:19])=[CH:25][CH:24]=3)[NH:26][C:13]=2[CH3:14])[CH:10]=1)[CH3:2]

Participants

3

Reactant 2

HCID 75331m-Chlorophenylhydrazine hydrochlorideHCID 667649843-Methyl-5-(2-oxo-propylsulfanyl)-benzoic acid ethyl ester

Product 1

HCID 667655633-(6-Chloro-2-methyl-1H-indol-3-ylsulfanyl)-5-methyl-benzoic acid ethyl ester

Procedure

Prepared according to the procedure described in Example 2, Step 1, using the following starting materials: 3-Methyl-5-(2-oxo-propylsulfanyl)-benzoic acid ethyl ester and 3-chlorophenylhydrazine hydrochloride.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-a326e0b4467d4333acb03f8018ad1aa4
Source dataset
uspto-grants-2015_04
Patent number
US09000025B2

Reaction notes

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