1H-Pyrazole, 4-bromo-1-methyl- → HCID 66765413, compound

HRID 1466848Notes

Reaction equation

HRID 1466848 reaction equation
[CH2:1]([O:3][C:4](=[O:27])[C:5]1[CH:10]=[C:9]([C:11]([F:14])([F:13])[F:12])[CH:8]=[C:7]([S:15][C:16]2[C:24]3[C:19](=[CH:20][C:21]([Cl:25])=[CH:22][CH:23]=3)[NH:18][C:17]=2[CH3:26])[CH:6]=1)[CH3:2].Br[C:29]1[CH:30]=[N:31][N:32]([CH3:34])[CH:33]=1>>[CH2:1]([O:3][C:4](=[O:27])[C:5]1[CH:10]=[C:9]([C:11]([F:13])([F:14])[F:12])[CH:8]=[C:7]([S:15][C:16]2[C:24]3[C:19](=[CH:20][C:21]([Cl:25])=[CH:22][CH:23]=3)[N:18]([C:29]3[CH:30]=[N:31][N:32]([CH3:34])[CH:33]=3)[C:17]=2[CH3:26])[CH:6]=1)[CH3:2]

Participants

3

Reactant 2

HCID 1674331H-Pyrazole, 4-bromo-1-methyl-HCID 66765411HCID 66765411, compound

Product 1

HCID 66765413HCID 66765413, compound

Procedure

Prepared according to the procedure described in Example 42, Step 4, using the following starting materials: 3-(6-Chloro-2-methyl-1H-indol-3-ylsulfanyl)-5-trifluoromethyl-benzoic acid ethyl ester and 4-bromo-1-methylpyrazole.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-46b7d107731a4fe79a68982f95df4df7
Source dataset
uspto-grants-2015_04
Patent number
US09000025B2

Reaction notes

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