3-Bromo-5-methylpyridine → 3-[6-Chloro-2-methyl-1-(5-methyl-pyridin-3-yl)-1H-indol-3-ylsulfanyl]-benzoic acid ethyl ester

HRID 1466851Notes

Reaction equation

HRID 1466851 reaction equation
[CH2:1]([O:3][C:4](=[O:24])[C:5]1[CH:10]=[CH:9][C:8](C)=[C:7]([S:12][C:13]2[C:21]3[C:16](=[CH:17][C:18]([Cl:22])=[CH:19][CH:20]=3)[NH:15][C:14]=2[CH3:23])[CH:6]=1)[CH3:2].Br[C:26]1[CH:27]=[N:28][CH:29]=[C:30]([CH3:32])[CH:31]=1>>[CH2:1]([O:3][C:4](=[O:24])[C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([S:12][C:13]2[C:21]3[C:16](=[CH:17][C:18]([Cl:22])=[CH:19][CH:20]=3)[N:15]([C:26]3[CH:27]=[N:28][CH:29]=[C:30]([CH3:32])[CH:31]=3)[C:14]=2[CH3:23])[CH:6]=1)[CH3:2]

Participants

3

Reactant 2

HCID 8177133-Bromo-5-methylpyridineHCID 667655163-(6-Chloro-2-methyl-1H-indol-3-ylsulfanyl)-4-methyl-benzoic acid ethyl ester

Product 1

HCID 667648453-[6-Chloro-2-methyl-1-(5-methyl-pyridin-3-yl)-1H-indol-3-ylsulfanyl]-benzoic acid ethyl ester

Procedure

Prepared according to the procedure described in Example 42, Step 4, using the following starting materials: 3-(6-Chloro-2-methyl-1H-indol-3-ylsulfanyl)-4-methyl-benzoic acid ethyl ester and 3-bromo-5-methyl-pyridine

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-4609fcf0bffd4f36aaeec075c290e07f
Source dataset
uspto-grants-2015_04
Patent number
US09000025B2

Reaction notes

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