4-Bromo-1,3-dimethyl-1H-pyrazole → 3-[6-Chloro-1-(1,3-dimethyl-1H-pyrazol-4-yl)-2-methyl-1H-indol-3-ylsulfanyl]-benzoic acid ethyl ester

HRID 1466855ノート

反応式

HRID 1466855 の反応式
[CH2:1]([O:3][C:4](=[O:23])[C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([S:11][C:12]2[C:20]3[C:15](=[CH:16][C:17]([Cl:21])=[CH:18][CH:19]=3)[NH:14][C:13]=2[CH3:22])[CH:6]=1)[CH3:2].Br[C:25]1[C:26]([CH3:31])=[N:27][N:28]([CH3:30])[CH:29]=1>>[CH2:1]([O:3][C:4](=[O:23])[C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([S:11][C:12]2[C:20]3[C:15](=[CH:16][C:17]([Cl:21])=[CH:18][CH:19]=3)[N:14]([C:25]3[C:26]([CH3:31])=[N:27][N:28]([CH3:30])[CH:29]=3)[C:13]=2[CH3:22])[CH:6]=1)[CH3:2]

参加物

3

反応物 2

HCID 126154164-Bromo-1,3-dimethyl-1H-pyrazoleHCID 667654983-(6-Chloro-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid ethyl ester

生成物 1

HCID 667652033-[6-Chloro-1-(1,3-dimethyl-1H-pyrazol-4-yl)-2-methyl-1H-indol-3-ylsulfanyl]-benzoic acid ethyl ester

実験手順

Prepared according to the procedure described in Example 55, Step 2 using the following starting materials: 3-(6-chloro-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid ethyl ester and 4-Bromo-1,3-dimethyl-1H-pyrazole.

後処理

  1. customPrepared

出典と根拠

ORDレコード
ord-44146301ba8642c1bf90fd5132f8c237
出典データセット
uspto-grants-2015_04
特許番号
US09000025B2

反応ノート

読み込み中…