4-Bromo-1-ethyl-1H-pyrazole → HCID 66765415, compound

HRID 1466873Notes

Reaction equation

HRID 1466873 reaction equation
[CH2:1]([O:3][C:4]([C:6]1([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([S:15][C:16]3[C:24]4[C:19](=[CH:20][C:21]([Cl:25])=[CH:22][CH:23]=4)[NH:18][C:17]=3[CH3:26])[CH:10]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2].Br[C:28]1[CH:29]=[N:30][N:31]([CH2:33][CH3:34])[CH:32]=1>>[CH2:1]([O:3][C:4]([C:6]1([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([S:15][C:16]3[C:24]4[C:19](=[CH:20][C:21]([Cl:25])=[CH:22][CH:23]=4)[N:18]([C:28]4[CH:29]=[N:30][N:31]([CH2:33][CH3:34])[CH:32]=4)[C:17]=3[CH3:26])[CH:10]=2)[CH2:7][CH2:8]1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 125652014-Bromo-1-ethyl-1H-pyrazoleHCID 66765116HCID 66765116, compound

Product 1

HCID 66765415HCID 66765415, compound

Procedure

Prepared according to the procedure described in Example 42, Step 4, using the following starting materials: 1-[3-(6-Chloro-2-methyl-1H-indol-3-ylsulfanyl)-phenyl]-cyclopropanecarboxylic acid ethyl ester and 4-bromo-1-ethylpyrazole.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-d6baf773a3cb4cafb106c4ff33b8b31a
Source dataset
uspto-grants-2015_04
Patent number
US09000025B2

Reaction notes

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