4-Bromo-1-ethyl-1H-pyrazole → HCID 66765623, compound

HRID 1466877Notes

Reaction equation

HRID 1466877 reaction equation
[CH3:1][O:2][C:3](=[O:23])[C:4]1[CH:9]=[C:8]([S:10][C:11]2[C:19]3[C:14](=[CH:15][C:16]([Cl:20])=[CH:17][CH:18]=3)[NH:13][C:12]=2[CH3:21])[CH:7]=[CH:6][C:5]=1[F:22].Br[C:25]1[CH:26]=[N:27][N:28]([CH2:30][CH3:31])[CH:29]=1>>[CH3:1][O:2][C:3](=[O:23])[C:4]1[CH:9]=[C:8]([S:10][C:11]2[C:19]3[C:14](=[CH:15][C:16]([Cl:20])=[CH:17][CH:18]=3)[N:13]([C:25]3[CH:26]=[N:27][N:28]([CH2:30][CH3:31])[CH:29]=3)[C:12]=2[CH3:21])[CH:7]=[CH:6][C:5]=1[F:22]

Participants

3

Reactant 2

HCID 125652014-Bromo-1-ethyl-1H-pyrazoleHCID 66765288HCID 66765288, compound

Product 1

HCID 66765623HCID 66765623, compound

Procedure

Prepared according to the procedure described in Example 55, Step 2 using the following starting materials: 5-(6-Chloro-2-methyl-1H-indol-3-ylsulfanyl)-2-fluoro-benzoic acid methyl ester and 4-bromo-1-ethyl-1H-pyrazole.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-fdaa125fbfe242f0b926a8a4215a3158
Source dataset
uspto-grants-2015_04
Patent number
US09000025B2

Reaction notes

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