m-Chlorophenylhydrazine hydrochloride → [2-(6-Chloro-2-methyl-1H-indol-3-ylsulfanyl)-phenyl]-acetic acid

HRID 1466892Notes

Reaction equation

HRID 1466892 reaction equation
O=[C:2]([CH3:15])[CH2:3][S:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[CH2:11][C:12]([OH:14])=[O:13].Cl.[Cl:17][C:18]1[CH:19]=[C:20]([NH:24]N)[CH:21]=[CH:22][CH:23]=1>>[Cl:17][C:18]1[CH:19]=[C:20]2[C:21]([C:3]([S:4][C:5]3[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=3[CH2:11][C:12]([OH:14])=[O:13])=[C:2]([CH3:15])[NH:24]2)=[CH:22][CH:23]=1

Participants

3

Reactant 2

HCID 75331m-Chlorophenylhydrazine hydrochlorideHCID 66764972[2-(2-Oxo-propylsulfanyl)-phenyl]-acetic acid

Product 1

HCID 56839997[2-(6-Chloro-2-methyl-1H-indol-3-ylsulfanyl)-phenyl]-acetic acid

Procedure

Prepared according to the procedure described in Example 2, Step 1, using the following starting materials: [2-(2-oxo-propylsulfanyl)-phenyl]-acetic acid and 3-chlorophenylhydrazine hydrochloride.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-e52ec2936be345269bde19e136665e73
Source dataset
uspto-grants-2015_04
Patent number
US09000025B2

Reaction notes

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