Hydrazine, (4-chlorophenyl)-, hydrochloride (1:1) → [3-(5-Chloro-2-methyl-1H-indol-3-ylsulfanyl)-phenyl]-acetic acid

HRID 1466895Notes

Reaction equation

HRID 1466895 reaction equation
O=[C:2]([CH3:15])[CH2:3][S:4][C:5]1[CH:6]=[C:7]([CH2:11][C:12]([OH:14])=[O:13])[CH:8]=[CH:9][CH:10]=1.Cl.[Cl:17][C:18]1[CH:23]=[CH:22][C:21]([NH:24]N)=[CH:20][CH:19]=1>>[Cl:17][C:18]1[CH:23]=[C:22]2[C:21](=[CH:20][CH:19]=1)[NH:24][C:2]([CH3:15])=[C:3]2[S:4][C:5]1[CH:6]=[C:7]([CH2:11][C:12]([OH:14])=[O:13])[CH:8]=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 71600Hydrazine, (4-chlorophenyl)-, hydrochloride (1:1)HCID 66765032[3-(2-Oxo-propylsulfanyl)-phenyl]-acetic acid

Product 1

HCID 66765396[3-(5-Chloro-2-methyl-1H-indol-3-ylsulfanyl)-phenyl]-acetic acid

Procedure

Prepared according to the procedure described in Example 2, Step 1, using the following starting materials: [3-(2-oxo-propylsulfanyl)-phenyl]-acetic acid and 4-chlorophenylhydrazine hydrochloride.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-b5f831a7828e4e5c8734d047370e3c72
Source dataset
uspto-grants-2015_04
Patent number
US09000025B2

Reaction notes

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