Methyl iodide → [3-(5-Chloro-1,2-dimethyl-1H-indol-3-ylsulfanyl)-phenyl]-acetic acid

HRID 1466903Notes

Reaction equation

HRID 1466903 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6]([CH3:11])=[C:5]2[S:12][C:13]1[CH:14]=[C:15]([CH2:19][C:20]([OH:22])=[O:21])[CH:16]=[CH:17][CH:18]=1.I[CH3:24]>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([CH3:24])[C:6]([CH3:11])=[C:5]2[S:12][C:13]1[CH:14]=[C:15]([CH2:19][C:20]([OH:22])=[O:21])[CH:16]=[CH:17][CH:18]=1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 66765396[3-(5-Chloro-2-methyl-1H-indol-3-ylsulfanyl)-phenyl]-acetic acid

Product 1

HCID 56840004[3-(5-Chloro-1,2-dimethyl-1H-indol-3-ylsulfanyl)-phenyl]-acetic acid

Procedure

Prepared according to the procedure described in Example 5, Step 2, using the following starting materials: [3-(5-chloro-2-methyl-1H-indol-3-ylsulfanyl)-phenyl]-acetic acid and iodomethane

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-033205b1b1fa41c381fa281a3f196100
Source dataset
uspto-grants-2015_04
Patent number
US09000025B2

Reaction notes

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