HCID 66765609, compound → HCID 66764894, compound

Participants

Reaction Steps

1-Benzyl-3-(3-bromo-phenylsulfanyl)-6-chloro-1H-indole-2-carboxylic acid (from the previous step) was dissolved in quinoline (5 mL) then copper (0.120 g, 2 mmol) was added and the reaction was placed in the microwave for 10 minutes at 150° C., and this heating was repeated 3 additional times. The reaction was submitted to standard workup procedures then purified by silica gel chromatography (0-20% EtOAc in hexanes) to provide the title compound.

Provenance & Evidence