(3-Chloro-2-methylphenyl)hydrazine hydrochloride → 3-(6-Chloro-2,7-dimethyl-1H-indol-3-ylsulfanyl)-benzoic acid ethyl ester

HRID 1466919Notes

Reaction equation

HRID 1466919 reaction equation
[CH2:1]([O:3][C:4](=[O:16])[C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([S:11][CH2:12][C:13](=O)[CH3:14])[CH:6]=1)[CH3:2].Cl.[Cl:18][C:19]1[C:20]([CH3:27])=[C:21]([NH:25]N)[CH:22]=[CH:23][CH:24]=1>>[CH2:1]([O:3][C:4](=[O:16])[C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([S:11][C:12]2[C:22]3[C:21](=[C:20]([CH3:27])[C:19]([Cl:18])=[CH:24][CH:23]=3)[NH:25][C:13]=2[CH3:14])[CH:6]=1)[CH3:2]

Participants

3

Reactant 2

HCID 12732296(3-Chloro-2-methylphenyl)hydrazine hydrochlorideHCID 667651013-(2-Oxo-propylsulfanyl)-benzoic acid ethyl ester

Product 1

HCID 667647213-(6-Chloro-2,7-dimethyl-1H-indol-3-ylsulfanyl)-benzoic acid ethyl ester

Procedure

Prepared according to the procedure described in Example 2, step 1, using the following starting materials: 3-(2-Oxo-propylsulfanyl)-benzoic acid ethyl ester and (3-Chloro-2-methyl-phenyl)-hydrazine hydrochloride.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-7fcb12332ea344d69eeb372c2bb44962
Source dataset
uspto-grants-2015_04
Patent number
US09000025B2

Reaction notes

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