m-Chlorophenylhydrazine hydrochloride → [4-(6-Chloro-2-methyl-1H-indol-3-ylsulfanyl)-phenyl]-acetic acid ethyl ester

HRID 1466928Notes

Reaction equation

HRID 1466928 reaction equation
[CH2:1]([O:3][C:4](=[O:17])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([S:12][CH2:13][C:14](=O)[CH3:15])=[CH:8][CH:7]=1)[CH3:2].Cl.[Cl:19][C:20]1[CH:21]=[C:22]([NH:26]N)[CH:23]=[CH:24][CH:25]=1>>[CH2:1]([O:3][C:4](=[O:17])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([S:12][C:13]2[C:23]3[C:22](=[CH:21][C:20]([Cl:19])=[CH:25][CH:24]=3)[NH:26][C:14]=2[CH3:15])=[CH:8][CH:7]=1)[CH3:2]

Participants

3

Reactant 2

HCID 75331m-Chlorophenylhydrazine hydrochlorideHCID 66764764Ethyl 2-(4-(2-oxopropylthio)phenyl)acetate

Product 1

HCID 66765689[4-(6-Chloro-2-methyl-1H-indol-3-ylsulfanyl)-phenyl]-acetic acid ethyl ester

Procedure

Prepared according to the procedure described in Example 2, Step 1, using the following starting materials: [4-(2-Oxo-propylsulfanyl)-phenyl]-acetic acid ethyl ester and 3-chlorophenylhydrazine hydrochloride.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-e3087d77ee96467e829d0fd877ac8105
Source dataset
uspto-grants-2015_04
Patent number
US09000025B2

Reaction notes

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