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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1466936Generated: November 1, 2026

1-Cyclopropyl-4-iodo-1H-pyrazole → 3-[6-Chloro-1-(1-cyclopropyl-1H-pyrazol-4-yl)-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl]-benzoic acid ethyl ester

https://huagongshe.com/reaction/1466936

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Cyclopropyl-4-iodo-1H-pyrazoleHCID 57516618—
Reactant3-(6-Chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid ethyl esterHCID 66765504—
Product3-[6-Chloro-1-(1-cyclopropyl-1H-pyrazol-4-yl)-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl]-benzoic acid ethyl esterHCID 66765003—

Reaction Steps

Prepared according to the procedure described in Example 55, Step 2 using the following starting materials: 3-(6-chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid ethyl ester and 1-cyclopropyl-4-iodo-1H-pyrazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000025B2
Source datasetuspto-grants-2015_04
ORD IDord-ae5a89b923044cc3bb3d7930b419b184
Source noteuspto-grants-2015_04