HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-1-(2-(T-butyldimethylsilyloxy)ethyl)pyrazole → 3-(1-{1-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-1H-pyrazol-4-yl}-6-chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-1-(2-(T-butyldimethylsilyloxy)ethyl)pyrazole | HCID 46739778 | — |
| Reactant | 3-(6-Chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid ethyl ester | HCID 66765504 | — |
| Product | 3-(1-{1-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-1H-pyrazol-4-yl}-6-chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid ethyl ester | HCID 66765209 | — |
Reaction Steps
Prepared according to the procedure described in Example 55, Step 2 using the following starting materials: 3-(6-chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid ethyl ester and 4-Bromo-1-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-1H-pyrazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09000025B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-205a90181f584a0da4d80e858c65a319 |
| Source note | uspto-grants-2015_04 |