1-Ethyl-3-iodo-1H-pyrazole → HCID 66765482, compound

HRID 1466945Notes

Reaction equation

HRID 1466945 reaction equation
[CH2:1]([O:3][C:4](=[O:24])[C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([S:11][C:12]2[C:20]3[C:15](=[C:16]([F:22])[C:17]([Cl:21])=[CH:18][CH:19]=3)[NH:14][C:13]=2[CH3:23])[CH:6]=1)[CH3:2].[CH2:25]([N:27]1[CH:31]=[CH:30][C:29](I)=[N:28]1)[CH3:26]>>[CH2:1]([O:3][C:4](=[O:24])[C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([S:11][C:12]2[C:20]3[C:15](=[C:16]([F:22])[C:17]([Cl:21])=[CH:18][CH:19]=3)[N:14]([C:29]3[CH:30]=[CH:31][N:27]([CH2:25][CH3:26])[N:28]=3)[C:13]=2[CH3:23])[CH:6]=1)[CH3:2]

Participants

3

Reactant 2

HCID 509989441-Ethyl-3-iodo-1H-pyrazoleHCID 667655043-(6-Chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid ethyl ester

Product 1

HCID 66765482HCID 66765482, compound

Procedure

Prepared according to the procedure described in Example 55, Step 2 using the following starting materials: 3-(6-chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid ethyl ester and 1-ethyl-3-iodo-1H-pyrazole.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-50898afd8ec241bf8add0b1f033c20b0
Source dataset
uspto-grants-2015_04
Patent number
US09000025B2

Reaction notes

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