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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1466950Generated: October 29, 2026

4-Bromo-1-ethyl-1H-pyrazole → 3-[6-Chloro-1-(1-ethyl-1H-pyrazol-4-yl)-2-methyl-1H-indol-3-ylsulfanyl]-2-fluoro-benzoic acid ethyl ester

https://huagongshe.com/reaction/1466950

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-1-ethyl-1H-pyrazoleHCID 12565201—
Reactant3-(6-Chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-2-fluoro-benzoic acid ethyl esterHCID 66765429—
Product3-[6-Chloro-1-(1-ethyl-1H-pyrazol-4-yl)-2-methyl-1H-indol-3-ylsulfanyl]-2-fluoro-benzoic acid ethyl esterHCID 66765441—

Reaction Steps

Prepared according to the procedure described in Example 55, Step 2 using the following starting materials: 3-(6-chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-2-fluoro-benzoic acid ethyl ester and 4-bromo-1-ethyl-1H-pyrazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000025B2
Source datasetuspto-grants-2015_04
ORD IDord-9515c2e1739d40709c3e77119bd31584
Source noteuspto-grants-2015_04