Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl (ethoxymethylene)malonate → Ethyl 4-hydroxy-6-propoxyquinoline-3-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl (ethoxymethylene)malonate | HCID 6871 | — |
| 반응물 | Benzenamine, 4-propoxy- | HCID 78221 | — |
| 생성물 | Ethyl 4-hydroxy-6-propoxyquinoline-3-carboxylate | HCID 178458202 | — |
반응 단계
Prepared as in Example 1c from 4-propoxyaniline and diethyl 2-(ethoxymethylene)malonate as a white solid (65%). 1H NMR (400 MHz, DMSO-d6) δ 0.98 (t, J=7.2 Hz, 3H), 1.25 (t, J=7.2 Hz, 3H), 1.72-1.77 (m, 2H), 3.98 (t, J=6.0 Hz, 2H), 4.16-4.21 (m, 2H), 6.97-6.99 (m, 1H), 7.53-7.56 (m, 2H), 8.47 (d, J=5.2 Hz, 1H), 12.27 (s, 1H). MS 276 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09000054B2 |
| 출처 데이터셋 | uspto-grants-2015_04 |
| ORD ID | ord-bcfbf3ed5a2a4aafa37a8ebd22bad8c6 |
| 출처 메모 | uspto-grants-2015_04 |