HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopentylamine → N-cyclopentyl-3-hydroxy-2,2-dimethylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopentylamine | HCID 2906 | — |
| Reactant | 3-Hydroxy-2,2-dimethylpropionic acid | HCID 78548 | — |
| Product | N-cyclopentyl-3-hydroxy-2,2-dimethylpropanamide | HCID 66746460 | — |
Reaction Steps
Prepared as in Example 24a from hydroxypivalic acid and cyclopentyl amine as an orange oil (32%). 1H NMR (400 MHz, DMSO-d6) δ 1.00 (s, 6H), 1.32-1.40 (m, 2H), 1.43-1.49 (m, 2H), 1.57-1.65 (m, 2H), 1.73-1.81 (m, 2H), 3.34 (d, J=4.0 Hz, 2H), 3.98 (m, 1H), 4.87 (t, J=4.0 Hz, 1H), 7.22 (d, J=4.0 Hz, 1H). MS 186 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09000054B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-f6d1b253931e41fa9b2901d95e34ad67 |
| Source note | uspto-grants-2015_04 |