HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Benzodioxane-6-carboxylic Acid → (S)-ethyl 4-amino-5-(2-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)propoxy)-2-methylquinoline-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Benzodioxane-6-carboxylic Acid | HCID 2758833 | — |
| Reactant | (S)-ethyl 4-amino-5-(2-aminopropoxy)-2-methylquinoline-3-carboxylate | HCID 86658188 | — |
| Product | (S)-ethyl 4-amino-5-(2-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)propoxy)-2-methylquinoline-3-carboxylate | HCID 86658192 | — |
Reaction Steps
Prepared as in Example 24a from (S)-ethyl 4-amino-5-(2-aminopropoxy)-2-methyl-quinoline-3-carboxylate (Example 26b) and 2,3-dihydrobenzo[b][1,4]dioxine-6-carboxylic acid as brown solid. MS 466 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09000054B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-fbcbe05063d747bea17e4975ac01fdd2 |
| Source note | uspto-grants-2015_04 |