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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1467070Generated: October 26, 2026

3-(2-Hydroxyethoxy)-4-methoxybenzoic acid → (S)-ethyl 4-amino-5-(2-(3-(2-hydroxyethoxy)-4-methoxybenzamido)propoxy)-2-methylquinoline-3-carboxylate

https://huagongshe.com/reaction/1467070

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2-Hydroxyethoxy)-4-methoxybenzoic acidHCID 24694006—
Reactant(S)-ethyl 4-amino-5-(2-aminopropoxy)-2-methylquinoline-3-carboxylateHCID 86658188—
Product(S)-ethyl 4-amino-5-(2-(3-(2-hydroxyethoxy)-4-methoxybenzamido)propoxy)-2-methylquinoline-3-carboxylateHCID 86658195—

Reaction Steps

Prepared as in Example 24a from (S)-ethyl 4-amino-5-(2-aminopropoxy)-2-methyl-quinoline-3-carboxylate (Example 26b) and 3-(2-hydroxyethoxy)-4-methoxybenzoic acid as a brown solid. MS 498 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000054B2
Source datasetuspto-grants-2015_04
ORD IDord-50381bd1f1eb4d398b8c63065467b61a
Source noteuspto-grants-2015_04