HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetoacetate → (S)-ethyl 4-amino-5-(2-aminobutoxy)-2-methylquinoline-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | (S)-benzyl 1-(3-amino-2-cyanophenoxy)butan-2-ylcarbamate | HCID 86658219 | — |
| Product | (S)-ethyl 4-amino-5-(2-aminobutoxy)-2-methylquinoline-3-carboxylate | HCID 86658218 | — |
Reaction Steps
Prepared as in Example 2a from (S)-benzyl 1-(3-amino-2-cyanophenoxy)butan-2-ylcarbamate (Example 97c) and ethyl 3-oxobutanoate as brown solid (75%). MS 318 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09000054B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-c053139d354c4999b57346f1e7f9688a |
| Source note | uspto-grants-2015_04 |