2-Amino-1-butanol, (+)- → HCID 66745584, compound

HRID 1467094Notes

Reaction equation

HRID 1467094 reaction equation
[NH2:1][C@@H:2]([CH2:5][CH3:6])[CH2:3][OH:4].[NH2:7][C:8]1[CH:15]=[CH:14][CH:13]=[C:12](F)[C:9]=1[C:10]#[N:11]>>[NH2:7][C:8]1[CH:15]=[CH:14][CH:13]=[C:12]([O:4][CH2:3][C@@H:2]([NH2:1])[CH2:5][CH3:6])[C:9]=1[C:10]#[N:11]

Participants

3

Reactant 2

HCID 1200842-Amino-1-butanol, (+)-HCID 5226592-Amino-6-fluorobenzonitrile

Product 1

HCID 66745584HCID 66745584, compound

Procedure

Prepared as in Example 24d from (S)-2-aminobutan-1-ol and 2-amino-6-fluoro-benzonitrile as brown solid (73%). MS 206 (MH+).

Sources & evidence

ORD record
ord-023f3ba516db4962b3d474c3ebc3a2a9
Source dataset
uspto-grants-2015_04
Patent number
US09000054B2

Reaction notes

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