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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1467108Generated: October 27, 2026

Ethyl Acetoacetate → Ethyl 4-amino-5-((2-methoxycyclohexyl)oxy)-2-methylquinoline-3-carboxylate

https://huagongshe.com/reaction/1467108

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl AcetoacetateHCID 8868—
Reactant2-Amino-6-(2-methoxycyclohexyloxy)benzonitrileHCID 66746630—
ProductEthyl 4-amino-5-((2-methoxycyclohexyl)oxy)-2-methylquinoline-3-carboxylateHCID 66746044—

Reaction Steps

Prepared as in Example 2a from 2-Amino-6-(2-methoxycyclohexyloxy)benzonitrile (Example 109b) and ethyl 3-oxobutanoate as a pale yellow oil (16%). MS 359 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000054B2
Source datasetuspto-grants-2015_04
ORD IDord-5f11dd90ed8b4a1987c7be7ee1822700
Source noteuspto-grants-2015_04