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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1467110Generated: October 25, 2026

3-Hydroxybenzoic Acid → Ethyl 4-amino-5-((1-(3-hydroxybenzoyl)piperidin-3-yl)methoxy)-2-methylquinoline-3-carboxylate

https://huagongshe.com/reaction/1467110

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Hydroxybenzoic AcidHCID 7420—
ReactantEthyl 4-amino-2-methyl-5-(piperidin-3-ylmethoxy)quinoline-3-carboxylateHCID 66746012—
ProductEthyl 4-amino-5-((1-(3-hydroxybenzoyl)piperidin-3-yl)methoxy)-2-methylquinoline-3-carboxylateHCID 66746557—

Reaction Steps

Prepared as in Example 24a from ethyl 4-amino-2-methyl-5-(piperidin-3-ylmethoxy)-quinoline-3-carboxylate (Example 110b) and 3-hydroxybenzoic acid as a white solid (34%). MS 464 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000054B2
Source datasetuspto-grants-2015_04
ORD IDord-034a6e697e7c4595ba6e77becc5ca307
Source noteuspto-grants-2015_04