Piperidin-3-ylmethanol → HCID 66746105, compound

HRID 1467112Notes

Reaction equation

HRID 1467112 reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][CH:3]([CH2:7][OH:8])[CH2:2]1.[NH2:9][C:10]1[CH:17]=[CH:16][CH:15]=[C:14](F)[C:11]=1[C:12]#[N:13]>>[NH2:9][C:10]1[CH:17]=[CH:16][CH:15]=[C:14]([O:8][CH2:7][CH:3]2[CH2:4][CH2:5][CH2:6][NH:1][CH2:2]2)[C:11]=1[C:12]#[N:13]

Participants

3

Reactant 2

HCID 107308Piperidin-3-ylmethanolHCID 5226592-Amino-6-fluorobenzonitrile

Product 1

HCID 66746105HCID 66746105, compound

Procedure

Prepared as in Example 24d from 3-piperidinemethanol and 2-amino-6-fluoro-benzonitrile as a light yellow solid (27%). MS 232 (MH+).

Sources & evidence

ORD record
ord-bd997f4f11ec47efb0702d212b62dedb
Source dataset
uspto-grants-2015_04
Patent number
US09000054B2

Reaction notes

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