3-Hydroxybenzoic Acid → HCID 66746923, compound

HRID 1467113Notes

Reaction equation

HRID 1467113 reaction equation
[NH2:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][C:10]=2[O:12][CH2:13][CH:14]2[CH2:19][CH2:18][CH2:17][CH2:16][NH:15]2)[N:5]=[C:4]([CH3:20])[C:3]=1[C:21]([O:23][CH2:24][CH3:25])=[O:22].[OH:26][C:27]1[CH:28]=[C:29]([CH:33]=[CH:34][CH:35]=1)[C:30](O)=[O:31]>>[NH2:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][C:10]=2[O:12][CH2:13][CH:14]2[CH2:19][CH2:18][CH2:17][CH2:16][N:15]2[C:30](=[O:31])[C:29]2[CH:33]=[CH:34][CH:35]=[C:27]([OH:26])[CH:28]=2)[N:5]=[C:4]([CH3:20])[C:3]=1[C:21]([O:23][CH2:24][CH3:25])=[O:22]

Participants

3

Reactant 2

HCID 74203-Hydroxybenzoic AcidHCID 66746461HCID 66746461, compound

Product 1

HCID 66746923HCID 66746923, compound

Procedure

Prepared as in Example 24a from ethyl 4-amino-2-methyl-5-(piperidin-2-ylmethoxy)-quinoline-3-carboxylate (Example 111b) and 3-hydroxybenzoic acid as a white solid (28%). MS 464 (MH+).

Sources & evidence

ORD record
ord-af7473519dd448a5938fd2b29f16d6d5
Source dataset
uspto-grants-2015_04
Patent number
US09000054B2

Reaction notes

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